L35S (p.Leu35Ser) variant of NCF1 (Neutrophil cytosol factor 1)
L35S (p.Leu35Ser) in NCF1 (Neutrophil cytosol factor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L35S (p.Leu35Ser) variant details
- p.Leu35Ser
- gnomAD 7-74778326-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- CADD 5.66
- SIFT 0.00
- Population evidence available
- Structural context available
- NCF1 SH3 domain domainome 1.0: score -0.199
- Literature evidence available