V35F (p.Val35Phe) variant of NAT2 (Arylamine N-acetyltransferase 2)
V35F (p.Val35Phe) in NAT2 (Arylamine N-acetyltransferase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V35F (p.Val35Phe) variant details
- p.Val35Phe
- ExAC rs752047953
- TOPMed rs752047953
- gnomAD rs752047953
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.16
- CADD 15.80
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00019)
- Structural context available