T25S (p.Thr25Ser) variant of NAT2 (Arylamine N-acetyltransferase 2)
T25S (p.Thr25Ser) in NAT2 (Arylamine N-acetyltransferase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
T25S (p.Thr25Ser) variant details
- p.Thr25Ser
- Ensembl rs1800761112
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.13
- CADD 15.60
- PolyPhen-2 0.15
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available