I59F (p.Ile59Phe) variant of NAT2 (Arylamine N-acetyltransferase 2)
I59F (p.Ile59Phe) in NAT2 (Arylamine N-acetyltransferase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I59F (p.Ile59Phe) variant details
- p.Ile59Phe
- ESP rs374728016
- ExAC rs374728016
- TOPMed rs374728016
- gnomAD rs374728016
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.20
- CADD 10.30
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available