I27F (p.Ile27Phe) variant of NAT1 (Arylamine N-acetyltransferase 1)
I27F (p.Ile27Phe) in NAT1 (Arylamine N-acetyltransferase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
I27F (p.Ile27Phe) variant details
- p.Ile27Phe
- gnomAD 8-18222126-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.25
- CADD 22.30
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available