W11L (p.Trp11Leu) variant of MYO7A (Unconventional myosin-VIIa)
W11L (p.Trp11Leu) in MYO7A (Unconventional myosin-VIIa) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, published literature, and structural context.
W11L (p.Trp11Leu) variant details
- p.Trp11Leu
- gnomAD 11-77142722-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.875
- REVEL 0.93
- CADD 29.70
- PolyPhen-2 0.81
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available