V22G (p.Val22Gly) variant of MYO7A (Unconventional myosin-VIIa)
V22G (p.Val22Gly) in MYO7A (Unconventional myosin-VIIa) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
V22G (p.Val22Gly) variant details
- p.Val22Gly
- gnomAD rs1555051493
- Missense
- Variant Prioritization Score for Impact Estimate 0.807
- REVEL 0.92
- AlphaMissense 0.82
- MetaLR 0.77
- MetaSVM 0.69
- CADD 26.90
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available