Q37Q (p.Gln37Gln) variant of MYO7A (Unconventional myosin-VIIa)
Q37Q (p.Gln37Gln) in MYO7A (Unconventional myosin-VIIa) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
Q37Q (p.Gln37Gln) variant details
- p.Gln37Gln
- rs1461064082
- gnomAD 11-77142801-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.364
- AlphaMissense 0.35
- MetaLR 0.48
- MetaSVM -0.21
- CADD 8.93
- PolyPhen-2 0.60
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available