D21Y (p.Asp21Tyr) variant of MYO7A (Unconventional myosin-VIIa)
D21Y (p.Asp21Tyr) in MYO7A (Unconventional myosin-VIIa) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
D21Y (p.Asp21Tyr) variant details
- p.Asp21Tyr
- gnomAD 11-77142751-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.775
- REVEL 0.77
- CADD 26.30
- PolyPhen-2 0.85
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available