W61S (p.Trp61Ser) variant of MYO15A (Unconventional myosin-XV)
W61S (p.Trp61Ser) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
W61S (p.Trp61Ser) variant details
- p.Trp61Ser
- gnomAD 17-18118982-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- REVEL 0.54
- ESM-1b 0.00
- AlphaMissense 0.93
- CADD 26.30
- PolyPhen-2 0.53
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available