T65S (p.Thr65Ser) variant of MYO15A (Unconventional myosin-XV)
T65S (p.Thr65Ser) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
T65S (p.Thr65Ser) variant details
- p.Thr65Ser
- TOPMed rs1461872151
- gnomAD rs1461872151
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.36
- ESM-1b 0.00
- AlphaMissense 0.32
- CADD 22.70
- PolyPhen-2 0.08
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available