R41H (p.Arg41His) variant of MYO15A (Unconventional myosin-XV)
R41H (p.Arg41His) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R41H (p.Arg41His) variant details
- p.Arg41His
- ExAC rs751394944
- TOPMed rs751394944
- gnomAD rs751394944
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.42
- ESM-1b 0.00
- AlphaMissense 0.58
- CADD 24.50
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available