R41G (p.Arg41Gly) variant of MYO15A (Unconventional myosin-XV)
R41G (p.Arg41Gly) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
R41G (p.Arg41Gly) variant details
- p.Arg41Gly
- 1000Genomes rs200234990
- ExAC rs200234990
- TOPMed rs200234990
- gnomAD rs200234990
- Missense
- Variant Prioritization Score for Impact Estimate 0.517
- REVEL 0.50
- ESM-1b 0.00
- AlphaMissense 0.82
- CADD 23.50
- PolyPhen-2 0.62
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available