R35P (p.Arg35Pro) variant of MYO15A (Unconventional myosin-XV)
R35P (p.Arg35Pro) in MYO15A (Unconventional myosin-XV) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes structural context.
R35P (p.Arg35Pro) variant details
- p.Arg35Pro
- rs765495851
- ClinGen CA398589421
- ClinVar RCV001983828
- ExAC rs765495851
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- ESM-1b 0.00
- AlphaMissense 0.99
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available