R28W (p.Arg28Trp) variant of MYO15A (Unconventional myosin-XV)
R28W (p.Arg28Trp) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
R28W (p.Arg28Trp) variant details
- p.Arg28Trp
- cosmic curated COSV99231
- ExAC rs775791438
- TOPMed rs775791438
- gnomAD rs775791438
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.48
- ESM-1b 0.81
- AlphaMissense 0.88
- CADD 23.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available