P45A (p.Pro45Ala) variant of MYO15A (Unconventional myosin-XV)
P45A (p.Pro45Ala) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
P45A (p.Pro45Ala) variant details
- p.Pro45Ala
- gnomAD rs1164143800
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.33
- ESM-1b 0.00
- AlphaMissense 0.65
- CADD 21.30
- PolyPhen-2 0.44
- SIFT 0.03
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available