P26A (p.Pro26Ala) variant of MYO15A (Unconventional myosin-XV)
P26A (p.Pro26Ala) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
P26A (p.Pro26Ala) variant details
- p.Pro26Ala
- ESP rs372395052
- ExAC rs372395052
- TOPMed rs372395052
- gnomAD rs372395052
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.29
- ESM-1b 0.00
- AlphaMissense 0.49
- CADD 15.70
- PolyPhen-2 0.30
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 0.00017)
- Structural context available