P23R (p.Pro23Arg) variant of MYO15A (Unconventional myosin-XV)
P23R (p.Pro23Arg) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
P23R (p.Pro23Arg) variant details
- p.Pro23Arg
- gnomAD rs2045834954
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.32
- ESM-1b 1.00
- AlphaMissense 0.51
- CADD 21.60
- PolyPhen-2 0.29
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available