P21S (p.Pro21Ser) variant of MYO15A (Unconventional myosin-XV)
P21S (p.Pro21Ser) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
P21S (p.Pro21Ser) variant details
- p.Pro21Ser
- gnomAD 17-18118861-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.28
- ESM-1b 0.07
- AlphaMissense 0.31
- CADD 15.10
- PolyPhen-2 0.19
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available