P21Q (p.Pro21Gln) variant of MYO15A (Unconventional myosin-XV)
P21Q (p.Pro21Gln) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
P21Q (p.Pro21Gln) variant details
- p.Pro21Gln
- gnomAD 17-18118862-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.21
- ESM-1b 0.00
- AlphaMissense 0.26
- CADD 13.80
- PolyPhen-2 0.10
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available