K46N (p.Lys46Asn) variant of MYO15A (Unconventional myosin-XV)
K46N (p.Lys46Asn) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
K46N (p.Lys46Asn) variant details
- p.Lys46Asn
- cosmic curated COSV52754
- ExAC rs755813626
- TOPMed rs755813626
- gnomAD rs755813626
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.36
- ESM-1b 0.47
- AlphaMissense 0.96
- CADD 24.50
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available