K25R (p.Lys25Arg) variant of MYO15A (Unconventional myosin-XV)
K25R (p.Lys25Arg) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
K25R (p.Lys25Arg) variant details
- p.Lys25Arg
- gnomAD 17-18118874-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.37
- ESM-1b 0.00
- AlphaMissense 0.35
- CADD 22.90
- PolyPhen-2 0.88
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available