K10T (p.Lys10Thr) variant of MYO15A (Unconventional myosin-XV)
K10T (p.Lys10Thr) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
K10T (p.Lys10Thr) variant details
- p.Lys10Thr
- gnomAD rs1207229062
- Missense
- Variant Prioritization Score for Impact Estimate 0.513
- REVEL 0.50
- ESM-1b 0.41
- AlphaMissense 0.52
- CADD 24.80
- PolyPhen-2 0.54
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available