K10R (p.Lys10Arg) variant of MYO15A (Unconventional myosin-XV)
K10R (p.Lys10Arg) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
K10R (p.Lys10Arg) variant details
- p.Lys10Arg
- gnomAD 17-18118829-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.38
- ESM-1b 0.71
- AlphaMissense 0.25
- CADD 22.30
- PolyPhen-2 0.27
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available