K10P (p.Lys10Pro) variant of MYO15A (Unconventional myosin-XV)
K10P (p.Lys10Pro) in MYO15A (Unconventional myosin-XV) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
K10P (p.Lys10Pro) variant details
- p.Lys10Pro
- rs1319049564
- gnomAD 17-18118824-GAAGA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.574
- CADD 26.50
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available