G66S (p.Gly66Ser) variant of MYO15A (Unconventional myosin-XV)
G66S (p.Gly66Ser) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G66S (p.Gly66Ser) variant details
- p.Gly66Ser
- cosmic curated COSV52753
- TOPMed rs1244935895
- gnomAD rs1244935895
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.26
- ESM-1b 0.00
- AlphaMissense 0.33
- CADD 23.70
- PolyPhen-2 0.85
- SIFT 0.05
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available