G66D (p.Gly66Asp) variant of MYO15A (Unconventional myosin-XV)
G66D (p.Gly66Asp) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
G66D (p.Gly66Asp) variant details
- p.Gly66Asp
- gnomAD 17-18118997-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.33
- ESM-1b 0.00
- AlphaMissense 0.77
- CADD 24.60
- PolyPhen-2 0.79
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available