G32E (p.Gly32Glu) variant of MYO15A (Unconventional myosin-XV)
G32E (p.Gly32Glu) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G32E (p.Gly32Glu) variant details
- p.Gly32Glu
- cosmic curated COSV52766
- Missense
- Variant Prioritization Score for Impact Estimate 0.478
- REVEL 0.34
- ESM-1b 0.00
- AlphaMissense 0.96
- CADD 25.00
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available