F59I (p.Phe59Ile) variant of MYO15A (Unconventional myosin-XV)
F59I (p.Phe59Ile) in MYO15A (Unconventional myosin-XV) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes structural context.
F59I (p.Phe59Ile) variant details
- p.Phe59Ile
- rs933253559
- ClinGen CA288413177
- ClinVar RCV001994437
- Ensembl rs933253559
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- ESM-1b 0.00
- AlphaMissense 0.90
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available