E24G (p.Glu24Gly) variant of MYO15A (Unconventional myosin-XV)
E24G (p.Glu24Gly) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
E24G (p.Glu24Gly) variant details
- p.Glu24Gly
- cosmic curated COSV11322
- gnomAD rs1172409837
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.43
- ESM-1b 0.28
- AlphaMissense 0.54
- CADD 23.20
- PolyPhen-2 0.39
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available