E24D (p.Glu24Asp) variant of MYO15A (Unconventional myosin-XV)
E24D (p.Glu24Asp) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
E24D (p.Glu24Asp) variant details
- p.Glu24Asp
- Ensembl rs532827422
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.40
- ESM-1b 0.35
- AlphaMissense 0.64
- CADD 22.70
- PolyPhen-2 0.55
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available