E22G (p.Glu22Gly) variant of MYO15A (Unconventional myosin-XV)
E22G (p.Glu22Gly) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
E22G (p.Glu22Gly) variant details
- p.Glu22Gly
- gnomAD 17-18118865-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.33
- ESM-1b 0.00
- AlphaMissense 0.47
- CADD 23.80
- PolyPhen-2 0.48
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available