D42Y (p.Asp42Tyr) variant of MYO15A (Unconventional myosin-XV)
D42Y (p.Asp42Tyr) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
D42Y (p.Asp42Tyr) variant details
- p.Asp42Tyr
- gnomAD 17-18118924-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.39
- ESM-1b 0.00
- AlphaMissense 0.85
- CADD 22.90
- PolyPhen-2 0.92
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available