A58T (p.Ala58Thr) variant of MYO15A (Unconventional myosin-XV)
A58T (p.Ala58Thr) in MYO15A (Unconventional myosin-XV) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A58T (p.Ala58Thr) variant details
- p.Ala58Thr
- Ensembl rs2045839091
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.19
- ESM-1b 0.00
- AlphaMissense 0.49
- CADD 16.70
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available