M77T (p.Met77Thr) variant of MYH7 (Myosin-7)
M77T (p.Met77Thr) in MYH7 (Myosin-7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
M77T (p.Met77Thr) variant details
- p.Met77Thr
- TOPMed rs1380485301
- gnomAD rs1380485301
- Missense
- Variant Prioritization Score for Impact Estimate 0.478
- REVEL 0.33
- ESM-1b 0.95
- AlphaMissense 0.36
- MetaLR 0.63
- MetaSVM 0.02
- CADD 23.50
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available