Y115C (p.Tyr115Cys) variant of MYH11 (Myosin-11)
Y115C (p.Tyr115Cys) in MYH11 (Myosin-11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
Y115C (p.Tyr115Cys) variant details
- p.Tyr115Cys
- gnomAD rs1465301521
- Missense
- Variant Prioritization Score for Impact Estimate 0.814
- REVEL 0.93
- CADD 29.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available