T70K (p.Thr70Lys) variant of MYH11 (Myosin-11)
T70K (p.Thr70Lys) in MYH11 (Myosin-11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
T70K (p.Thr70Lys) variant details
- p.Thr70Lys
- cosmic curated COSV55573
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- REVEL 0.40
- CADD 20.90
- PolyPhen-2 0.01
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available