L14P (p.Leu14Pro) variant of MYH11 (Myosin-11)
L14P (p.Leu14Pro) in MYH11 (Myosin-11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
L14P (p.Leu14Pro) variant details
- p.Leu14Pro
- cosmic curated COSV10517
- ExAC rs745386427
- gnomAD rs745386427
- Missense
- Variant Prioritization Score for Impact Estimate 0.823
- REVEL 0.94
- CADD 28.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available