D74G (p.Asp74Gly) variant of MYH11 (Myosin-11)
D74G (p.Asp74Gly) in MYH11 (Myosin-11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
D74G (p.Asp74Gly) variant details
- p.Asp74Gly
- TOPMed rs1454312109
- gnomAD rs1454312109
- Missense
- Variant Prioritization Score for Impact Estimate 0.8
- REVEL 0.91
- CADD 28.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available