T41S (p.Thr41Ser) variant of MYD88 (Q99836)
T41S (p.Thr41Ser) in MYD88 (Q99836) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
T41S (p.Thr41Ser) variant details
- p.Thr41Ser
- rs587778543
- ClinGen CA160951
- ClinVar RCV000121608
- ClinVar RCV002517600
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- CADD 8.31
- PolyPhen-2 0.01
- SIFT 1.00
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available