R40W (p.Arg40Trp) variant of MYD88 (Q99836)
R40W (p.Arg40Trp) in MYD88 (Q99836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R40W (p.Arg40Trp) variant details
- p.Arg40Trp
- ExAC rs778396641
- gnomAD rs778396641
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- CADD 24.50
- PolyPhen-2 0.87
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available