R40L (p.Arg40Leu) variant of MYD88 (Q99836)
R40L (p.Arg40Leu) in MYD88 (Q99836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R40L (p.Arg40Leu) variant details
- p.Arg40Leu
- ExAC rs749723040
- TOPMed rs749723040
- gnomAD rs749723040
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- CADD 22.00
- PolyPhen-2 0.39
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available