L22W (p.Leu22Trp) variant of MYD88 (Q99836)
L22W (p.Leu22Trp) in MYD88 (Q99836) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L22W (p.Leu22Trp) variant details
- p.Leu22Trp
- gnomAD 3-38138760-TC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.336
- CADD 23.50
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available