Q25H (p.Gln25His) variant of MYCN (N-myc proto-oncogene protein)
Q25H (p.Gln25His) in MYCN (N-myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
Q25H (p.Gln25His) variant details
- p.Gln25His
- ExAC rs764975322
- TOPMed rs764975322
- gnomAD rs764975322
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.27
- MetaLR 0.16
- MetaSVM -0.86
- CADD 24.40
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available