P10T (p.Pro10Thr) variant of MYCN (N-myc proto-oncogene protein)
P10T (p.Pro10Thr) in MYCN (N-myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
P10T (p.Pro10Thr) variant details
- p.Pro10Thr
- 1000Genomes rs577079213
- ExAC rs577079213
- gnomAD rs577079213
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.39
- MetaLR 0.22
- MetaSVM -0.94
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available