L24P (p.Leu24Pro) variant of MYCN (N-myc proto-oncogene protein)
L24P (p.Leu24Pro) in MYCN (N-myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
L24P (p.Leu24Pro) variant details
- p.Leu24Pro
- Ensembl rs2103323435
- Missense
- Variant Prioritization Score for Impact Estimate 0.538
- REVEL 0.54
- MetaLR 0.16
- MetaSVM -0.81
- CADD 29.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available