K15R (p.Lys15Arg) variant of MYCN (N-myc proto-oncogene protein)
K15R (p.Lys15Arg) in MYCN (N-myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
K15R (p.Lys15Arg) variant details
- p.Lys15Arg
- gnomAD rs1429263576
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.09
- MetaLR 0.06
- MetaSVM -1.11
- CADD 24.60
- PolyPhen-2 0.53
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available