D33N (p.Asp33Asn) variant of MYCN (N-myc proto-oncogene protein)
D33N (p.Asp33Asn) in MYCN (N-myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D33N (p.Asp33Asn) variant details
- p.Asp33Asn
- TOPMed rs1481041288
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.22
- MetaLR 0.06
- MetaSVM -1.08
- CADD 30.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available