D33G (p.Asp33Gly) variant of MYCN (N-myc proto-oncogene protein)
D33G (p.Asp33Gly) in MYCN (N-myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
D33G (p.Asp33Gly) variant details
- p.Asp33Gly
- Ensembl rs1558533634
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.32
- MetaLR 0.12
- MetaSVM -0.95
- CADD 32.00
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available