R5Q (p.Arg5Gln) variant of MYC (Myc proto-oncogene protein)
R5Q (p.Arg5Gln) in MYC (Myc proto-oncogene protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R5Q (p.Arg5Gln) variant details
- p.Arg5Gln
- cosmic curated COSV52368
- ExAC rs747141352
- TOPMed rs747141352
- gnomAD rs747141352
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available